Current Studies

Now enrolling

The research studies listed below are currently enrolling participants.
To inquire about our research studies, please contact Soe Mar by email at mars@wustl.edu

Environmental and Genetic Risk Factors for Pediatric Multiple Sclerosis Study

The purpose of the Environmental and Genetic Risk Factors for Pediatric Multiple Sclerosis Study (E & G in Peds MS, PI- Waubant) is to determine if risk factors identified for adult MS are also risk factors for pediatric MS and if there are interactions between risk factors. Participants must be 3 – 18 years old. The study is enrolling participants with multiple sclerosis or clinically isolated syndrome (CIS), as well as healthy controls. The study requires that participants come to 1 study visit at St. Louis Children’s Hospital, consent to having their medical data relating to their demyelinating disease entered into a database, provide a blood sample, and complete questionnaires. Participants (MS/CIS and healthy controls) will be compensated $50 for completing the study.
NOTE: Participants with MS or CIS disease onset more than 4 years ago are not eligible.

Pediatric Multiple Sclerosis and other Demyelinating Disease (PeMSDD) Database Study

The Pediatric Multiple Sclerosis and other Demyelinating Disease (PeMSDD) Database Study is sponsored by the Network of Pediatric Multiple Sclerosis Centers and the National Multiple Sclerosis Society. The purpose of the PeMSDD database study is to provide data on patients with MS and other demyelinating diseases to support hypothesis generation and study design development for clinical trials and observational studies. Participants who have been diagnosed or have a suspected onset of MS or other demyelinating disease before the age of 18 years old are eligible. Participants will consent to having their medical data relating to their demyelinating disease entered into the database. There are no study visits required.

Infectious and Autoimmune Encephalitis Study

The Infectious and Autoimmune Encephalitis Study is funded by URSA to differentiate infectious and autoimmune encephalitis by using next generation sequencing to identify pathogen, and to identify biomarkers which can predict cognitive outcome.

Biomarkers for Cognitive Outcomes in Children with CNS Demyelination Study

The purpose of the Biomarkers for Cognitive Outcomes in Children with CNS Demyelination Study is to attempt to identify biomarkers that can predict cognitive outcomes in children with MS and other demyelinating diseases.

Pediatric Treatment Trials